Thomas H Bugge Selected Research

Sarcoma (Soft Tissue Sarcoma)

1/2016	Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180.
12/2002	Plasminogen promotes sarcoma growth and suppresses the accumulation of tumor-infiltrating macrophages.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Thomas H Bugge Research Topics

Disease

44	Neoplasms (Cancer) 01/2022 - 02/2002
15	Anthrax 12/2020 - 02/2002
9	Inflammation (Inflammations) 01/2019 - 08/2005
7	Carcinogenesis 01/2017 - 06/2005
6	Fibrosis (Cirrhosis) 08/2020 - 06/2005
6	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/2019 - 11/2004
5	Pathologic Processes 03/2014 - 02/2004
4	Neoplasm Metastasis (Metastasis) 11/2020 - 11/2004
4	Carcinoma (Carcinomatosis) 02/2015 - 06/2005
4	Melanoma (Melanoma, Malignant) 09/2014 - 08/2003
4	Squamous Cell Carcinoma of Head and Neck 01/2011 - 11/2004
3	Atrophy 01/2022 - 01/2018
2	Afibrinogenemia (Fibrinogen Deficiency) 01/2022 - 01/2019
2	Peritonitis 01/2022 - 01/2019
2	Proteinuria 01/2022 - 01/2022
2	Osteosarcoma (Osteogenic Sarcoma) 11/2020 - 01/2016
2	Hemorrhage 11/2019 - 01/2018
2	Intestinal Failure 11/2019 - 01/2018
2	Idiopathic Pulmonary Fibrosis 01/2019 - 04/2016
2	Lung Injury 01/2019 - 04/2016
2	Infections 01/2016 - 04/2009
2	Sarcoma (Soft Tissue Sarcoma) 01/2016 - 12/2002
2	Dehydration (Water Stress) 05/2014 - 05/2002
2	Neural Tube Defects (Exencephaly) 01/2012 - 08/2009
2	Wounds and Injuries (Trauma) 05/2010 - 08/2008
2	Ichthyosis (Xeroderma) 06/2009 - 12/2007
2	Breast Neoplasms (Breast Cancer) 05/2007 - 01/2004
2	Hyperplasia 09/2005 - 08/2005
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2004 - 10/2004
1	Acute-Phase Reaction 01/2022
1	Alopecia (Baldness) 01/2022
1	Body Weight (Weight, Body) 01/2022
1	Edema (Dropsy) 01/2022
1	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2022
1	Thrombosis (Thrombus) 01/2022
1	Endotoxemia 01/2022
1	Periodontal Diseases (Periodontal Disease) 12/2021
1	Weight Loss (Weight Reduction) 01/2021
1	Renal Insufficiency (Renal Failure) 01/2021
1	Hyperkalemia 01/2021
1	Acidosis 01/2021
1	Inborn Genetic Diseases (Disease, Hereditary) 11/2019
1	Weight Gain 11/2019

Drug/Important Bio-Agent (IBA)

16	matriptaseIBA 11/2019 - 05/2002
15	Proteins (Proteins, Gene)FDA Link 10/2019 - 11/2004
14	Serine Proteases (Serine Protease)IBA 01/2022 - 05/2002
12	CollagenIBA 08/2020 - 12/2002
12	Peptide Hydrolases (Proteases)FDA Link 09/2017 - 02/2002
11	Urokinase-Type Plasminogen Activator (Urokinase)FDA Link 09/2017 - 01/2003
10	Matrix Metalloproteinases (MMPs)IBA 10/2019 - 06/2005
8	PlasminogenIBA 01/2022 - 06/2002
8	anthrax toxin (anthrax lethal factor)IBA 01/2019 - 06/2005
7	Plasminogen Activators (Plasminogen Activator)IBA 09/2014 - 12/2002
6	AntigensIBA 01/2022 - 04/2007
6	prostasinIBA 01/2022 - 10/2007
5	Endo180IBA 01/2016 - 06/2005
4	Matrix Metalloproteinase 14 (MT1-MMP)IBA 11/2020 - 09/2005
4	Collagen ReceptorsIBA 08/2020 - 09/2007
4	FurinIBA 10/2019 - 03/2008
4	FibrinIBA 03/2016 - 12/2002
4	GelatinasesIBA 01/2010 - 03/2008
4	Mitogen-Activated Protein KinasesIBA 01/2010 - 08/2003
4	Diphtheria ToxinIBA 07/2009 - 02/2002
3	EnzymesIBA 01/2022 - 02/2002
3	Fibrinolysin FDA Link 01/2019 - 09/2007
3	Metalloproteases (Metalloproteinases)IBA 01/2016 - 03/2007
3	anthrax toxin receptorsIBA 06/2012 - 10/2006
3	ExotoxinsIBA 07/2009 - 02/2002
2	CytokinesIBA 01/2022 - 07/2012
2	CAP1-6DIBA 01/2022 - 01/2012
2	SaltsIBA 01/2021 - 04/2013
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2020 - 01/2008
2	MucinsIBA 11/2019 - 01/2018
2	Protease Inhibitors (Protease Inhibitor)IBA 11/2019 - 05/2007
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 02/2015 - 02/2002
2	IntegrinsIBA 02/2015 - 02/2002
2	Mannose ReceptorIBA 03/2014 - 02/2012
2	TrypsinIBA 04/2009 - 06/2003
2	Urokinase Plasminogen Activator ReceptorsIBA 09/2007 - 12/2002
2	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 12/2004 - 10/2004
1	Tight Junction ProteinsIBA 01/2022
1	fibrin fragment D (D-dimer)IBA 01/2022
1	edema factorIBA 01/2022
1	Epithelial Cell Adhesion MoleculeIBA 01/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2022
1	Fibrinogen (Factor I)FDA Link 01/2022
1	Glycoproteins (Glycoprotein)IBA 01/2022
1	ClaudinsIBA 01/2022
1	Epithelial Sodium ChannelsIBA 01/2022
1	SodiumIBA 01/2022
1	Triamterene (Dyrenium)FDA LinkGeneric 01/2021
1	Bromodeoxyuridine (BrdU)IBA 01/2021
1	Phosphotransferases (Kinase)IBA 12/2020
1	InflammasomesIBA 12/2020
1	Phenobarbital (Luminal)FDA Link 11/2019
1	human airway trypsin-like proteaseIBA 11/2019
1	Collectins (Collectin)IBA 01/2019
1	Pharmaceutical PreparationsIBA 01/2019

Therapy/Procedure

8	Therapeutics 12/2016 - 08/2003
1	Intravenous Administration 10/2019